Publications

Chen ZL, Yu H, Yu WM, Pawlak R, Strickland S. Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor. J Cell Biol. 2008, Dec 29;183(7)::1299-1313. Article

Bennur S, B.S. Shankaranarayana Rao, Pawlak R, Strickland S, McEwen BS, Chattarji S. Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator. Neuroscience 2007, 144(1):8-16. Article

Pawlak R, B.S.Shankaranarayana Rao, Melchor JP, Chattarji S, McEwen B, Strickland S. Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus. Proc Natl Acad Sci U S A 2005, 112(50):18201-18206. Article

Pawlak, R., Melchor, J.P., Matys, T., Skrzypiec, A.E. & Strickland, S. Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors. Proc Natl Acad Sci U S A 2005, 102(2):443-448. Article

* Matys T, * Pawlak R, Matys E, Pavlides C, McEwen BS & Strickland S. Tissue plasminogen activator promotes the effects of corticotropin-releasing factor on the amygdala and anxiety-like behavior. Proc Natl Acad Sci U S A 2004, 101(46):16345-16350. * Co-first authors.. Article

Pawlak R, Magarinos AM, Melchor JP, McEwen B, Strickland S. Tissue-plasminogen activator in the amygdala is critical for anxiety-like behavior. Nature Neuroscience 2003, 6(2):168-174. Article

Melchor J.P, Pawlak R, Strickland S. The tPA/plasminogen proteolytic cascade accelerates Aß degradation and inhibits Aß-induced neurodegeneration. J Neurosci 2003, 23(26):8867- 8871. Article